From Laboratory to Industry Level: What is Crucial in Scale-up Processes?

Every distillation follows a tried and tested process - but when the quantities change significantly, familiar steps quickly become challenges. Although the requirements with large volumes are the same as on a small scale: precise execution, reproducible results and this in a short time. The Heidolph large scale evaporators of the Hei-VAP Industrial series are perfectly designed for a great deal of different distilling processes, from standard evaporation without vacuum control up to complex distillation processes with vacuum control.

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The quantity decides

The first step in upscaling is to determine the volume of the material to be processed. 

Our recommendation for small batch volumes up to 15 liters: our benchtop rotary evaporators. From the Hei-VAP Core, Expert, Ultimate to the Hei-VAP Expert Control and Hei-VAP Ultimate Control models, we have spent three decades redefining rotary evaporation to make your research easier, faster and more efficient. 

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Increased ease of use

Ergonomic handles, knobs with LED rings

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Leading system tightness

PTFE compound with FKM O-ring and double sealing lips for a maximum tightness and increased life span

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Purest results by innovative sealing technology

Glassware systems with no ground joints at the top of the condenser anymore; innovative ventilation and replenishment valves

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Extended application range due to improved components

FDA-compliant materials/tubings for all components in direct or indirect contact with the medium

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Higher performance

Up to 40% higher evaporation rates due to XL condensers

Our recommendation for larger batch volumes up to 50 liters: our large scale rotary evaporators Hei-VAP Industrial. Here, too, attention has been paid to a very high level of user-friendliness of the operating elements and more safety for an efficient increase in performance.

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We offer two large scale rotary evaporator models depending on your budget.

We will be happy to advise you!


Hei-VAP Industrial

For maximum performance and highest safety


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Hei-VAP Industrial B

For upscale applications

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Do you have questions or would you like advice?