All products

The new Solid.Line KBF-S climate chamber is a custom-made solution for long-term testing and accelerated stability testing for pharmaceutical products in accordance with the ICH Q1A guideline. The corrosion-free and condensation-free interior also ensures exceptionally stable temperature and moisture levels, even when fully loaded.
Benefits
• Homogeneous climate conditions thanks to APT.line™ preheating chamber
• Standard-compliant testing according to ICH Q1A
• Precise temperature and humidity control
Important characteristics
• Temperature range: 0 °C to +70 °C
• Humidity range: 20% to 80% RH
• APT.line™ preheating chamber technology
• Humidity regulation with capacitive humidity sensor and steam humidification
• LCD to display temperature and humidity along with additional information and alarms
• Internal data logger, measured values can be read out in open format via USB
• Unit self-test for comprehensive status analysis
• Inner chamber made completely of stainless steel
• 2 stainless steel racks, incl. shelf supports
• Access port with silicone plug, 30 mm, left
• Robust twin casters with brakes, from 240 L
• Class 3.1 independent temperature safety device (DIN 12880) with visual and audible temperature alarm
• Computer interface: Ethernet
• Independent water supply via tank

The BINDER CB series CO₂ incubator is the premium class among the CO₂ incubators. It is suitable for all sensitive incubation applications and ensures optimal cell growth. A BINDER CB series CO₂ incubator can perform complex cultivation experiments as well as specific enviromental conditions.
Benefits
• Maximum usable space with minimal footprint and excellent ease of use
• Minimum risk of contamination thanks to uncompromising hot-air sterilization
• Fanless, easy-to-clean hygienic interior without fixtures
• Stable pH values thanks to drift-free CO₂ IR sensor technology
• Low evaporation of the medium due to high levels of humidity and quick recovery time
Important characteristics
• Temperature range: +4 °C above ambient temperature to +60 °C
• Humidity range: 90 to 95% RH
• CO₂ control range: 0 to 20 vol.% CO₂
• Tried-and-tested anti-contamination concept with 180 °C hot air sterilization
• Optimized double-pan humidification system with condensation protection
• CO₂ gas-mixing jet with Venturi effect
• Hot-air sterilizable CO₂ sensor with single-beam infrared technology
• Intuitive touchscreen controller
• Internal data recording, can be read out in open format via USB interface
• Fail-safe CO₂ system for protecting the pH of cell cultures
• DuoDoor™ system: Unit door and glass door can be opened with one handle
• Tightly fitted inner door made of safety glass
• Lockable door handle
• Seamless inner chamber made of stainless steel with flanges as shelf support system
• Perforated shelves, stainless steel
• Troubleshooting system with visual and acoustic alarms
• Interfaces: Ethernet, USB, zero-voltage alarm contact
• Units can be stacked with stacking adapters; the CB is suitable for stacking with CBF and CB-S models of the same size

Refrigerated Circulators from the CORIO CP range are suitable for applications with a temperature range from -50°C to +200°C. The enhanced pump performance ensures they are suitable for easy temperature control tasks in combination with external applications.
• Models for internal and external applications
• Bright, white, easy-to-read display
• Very quiet
• Easy change-over from internal to external circulation and vice versa
• External pump connections (M16×1) pump capacity, infinitely adjustable
• USB interface
• R232 interface
• Space-saving cooling coil design provides more usable space in the bath tank
• Bath lid and drain tap included
• Removable ventilation grid
• Refrigeration unit without side vents
• System for low liquid level
• Class III (FL) according to DIN 12876-1
To adapt the CORIO Refrigerated / Heating Circulator to your individual application, we offer a comprehensive range of accessories (bath fluid, tubing, adapter and more)

Refrigerated / Heating Circulators of the CORIO series distinguish themselves with a great price-performance ratio. They are ideal for all standard tasks and routine work in laboratories and industry.
• Models for internal and external applications
• Bright, white, easy-to-read display
• Very quiet
• Easy change-over from internal to external circulation and vice versa
• External pump connections (M16×1)
• USB interface
• Space-saving cooling coil design provides more usable space in the bath tank
• Bath lid and drain tap included
• Removable ventilation grid
• Refrigeration unit without side vents
• Class III (FL) according to DIN 12876-1
To adapt the CORIO Refrigerated / Heating Circulator to your individual application, we offer a comprehensive range of accessories (bath fluid, tubing, adapter and more).

The MediLine range appliances are equipped with many features to guarantee the safety of stored products and temperature stability in the interior. High-quality materials and precise workmanship, extremely efficient refrigeration components as well as documentation and alarm functions ensure optimum storage of sensitive samples, chemicals and research materials.
• Maximum temperature consistency.
Maximum temperature stability in the interior is ensured by the dynamic cooling system with double ventilation. Very short defrost cycles allow the internal temperature to be kept almost constant during the defrost phases. All laboratory appliances are designed according to the EN 60068-3 standard with regard to maximum temperature stability and consistency
• Integrated digital controller.
The intuitive controller with integrated real-time clock allows the temperature to be set to 1/10°C accuracy. The large display allows improved temperature visibility at a glance. The keyboard is dirt resistant and easy to clean – to meet the most stringent hygiene requirements in the laboratory.
• Integrated alarm systems.
A visual and audible door alarm alerts the user to temperature deviations. An alarm is also raised if the door is open for longer than one minute or in the event of power failure.
• Integrated data memory.
The min/max temperature memory function stores the values for up to 41 days. In addition the alarm memory function records the last 3 alarm conditions with alarm type, date and time, duration and maximum temperature.
• Accurate 1-point calibration.
The digital controller includes a calibration function for extremely accurate temperature control and display. This permits compensation between the set temperature and the actual internal temperature. Positive or negative changes to the correction value can be made in steps of 0.1 K.
• Mains-independent power supply of the electronic controller.
In case of power failure, the electronic controller is powered by a battery. The memory continues to log the internal temperature for another 72 hours. If external alarm and monitoring systems have been connected, then data transfer to these is also maintained.
• External temperature sensor.
The laboratory appliances have an access port (diameter 7.0 mm) in the appliance ceiling which allows a temperature sensor to be positioned in the interior.
• External temperature and alarm documentation.
The laboratory appliances are equipped with a volt-free contact for alarm forwarding to an external remote warning system. In addition the appliances have an RS 485 interface which enables as many as 20 appliances to be networked with a central monitoring and alarm system.
• Energy-effi cient hot-gas defrost system/ No temperature spikes.
Defrost less often and faster: the controller calculates the optimum defrost cycles based on the compressor run-time. Then the fridges defrost in just 8 minutes and the freezers in just 12 minutes. The internal temperature is slightly lowered shortly before so it remains almost constant during the defrost cycle.
• Heavy-duty professional stable door.
Quick access, minimal cold loss, maintaining of product quality. Half-door appliances are ideal particularly with the frequent door opening which occurs in the pharmaceutical industry or the laboratory. Samples and compounds used more frequently are stored in the upper area for quick access while below there is plenty of space for materials and raw materials which are needed less frequently. Thanks to the stable doors with their self-closing mechanism, only a small amount of cold air escapes on opening and this helps to maintain temperature stability and therefore the quality of the goods stored over the long term.
• 5 years guarantee

Refrigerated / heating circulators of the CORIO series distinguish themselves with a great price-to-performance ratio. They are ideal for all standard tasks and routine work in laboratories and industry.
Product features:
• Models for internal and external applications
• Bright, white, easy-to-read display
• Very quiet
• Easy change-over from internal to external circulation and vice versa
• Integrated pump connection (M16×1)
• USB connection
• Space-saving cooling coil design provides more usable space in the bath tank
• Bath lid and drain tap included
• Removable ventilation grid
• Refrigeration unit without side vents
• Class III (FL) according to DIN 12876-1

Refrigerated / heating circulators of the CORIO series distinguish themselves with a great price-to-performance ratio. They are ideal for all standard tasks and routine work in laboratories and industry.
Product features:
• Models for internal and external applications
• Bright, white, easy-to-read display
• Very quiet
• Easy change-over from internal to external circulation and vice versa
• Integrated pump connection (M16×1)
• USB connection
• Space-saving cooling coil design provides more usable space in the bath tank
• Bath lid and drain tap included
• Removable ventilation grid
• Refrigeration unit without side vents
• Class III (FL) according to DIN 12876-1
• Refrigerant R290

Refrigerated circulators of the DYNEO series distinguish themselves with a great price-performance ratio. The instruments offer high heating/cooling capacities for short heat-up and cool-down times. The refrigerated circulators work precisely and reliably even at higher ambient temperatures up to +40 °C. Either in basic research, in material testing or in technical systems – the DYNEO refrigerated circulators offer functional solutions for every requirement and budget.
• Models suitable for internal and external applications
• Optimized cooling coil design provides more space in the bath
• Continuously adjustable, powerful pressure pump
• Supply pressure 0.7 bar
• Easy change-over from internal to external circulation and vice versa
• Large color TFT display, multi-lingual user interface
• Ease of use via central rotary dial
• Integrated programmer
• External Pt100 sensor connection
• USB data port
• RS232 interface or analog interfaces (optional)
• Built-in drain tap for easy and safe drainage

Refrigerated circulators of the DYNEO series distinguish themselves with a great price-performance ratio. The instruments offer high heating/cooling capacities for short heat-up and cool-down times. The refrigerated circulators work precisely and reliably even at higher ambient temperatures up to +40 °C. Either in basic research, in material testing or in technical systems – the DYNEO refrigerated circulators offer functional solutions for every requirement and budget.
• Models suitable for internal and external applications
• Optimized cooling coil design provides more space in the bath
• Continuously adjustable, powerful pressure pump
• Supply pressure 0.7 bar
• Easy change-over from internal to external circulation and vice versa
• Large color TFT display, multi-lingual user interface
• Ease of use via central rotary dial
• Integrated programmer
• External Pt100 sensor connection
• USB data port
• RS232 interface or analog interfaces (optional)
• Built-in drain tap for easy and safe drainage

Product features:
• Models for internal and external applications
• Bright, white, easy to read display
• Very quiet
• Easy switching between internal and external circulation
• Powerful and infinitely adjustable pressure pump
• Interfaces: R232, USB
• ATC: 3 Point Calibration
• Temperature control: PID1
• Setting the resolution of the LED temperature display °C: 0.1
• Class III (FL) according to DIN 12876-1
• Bath lid and drain tap included
• Removable ventilation grid
• Refrigeration unit without side vents
• Integrated pump connection M16×1
• Space-saving cooling coil design provides more usable space in the bath tank
• Early warning system for low liquid level

Includes:

• Magnetic stirrer Hei-PLATE Mix'n'Heat Expert (135 mm diameter) - Fast and precise heating - Without overshoot - For sample-friendly work
• Pt1000 temperature sensor for precise temperature regulation
• Pt1000 holder with cable device for securely attaching the temperature sensor
• Silicone protective cover for a longer lasting protection of your magnetic stirrer
• Also available with 145 mm plate on request

Product features:
• Models for internal and external applications
• Bright, white, easy to read display
• Very quiet
• Easy switching between internal and external circulation
• Powerful and infinitely adjustable pressure pump
• Interfaces: R232, USB
• ATC: 3 Point Calibration
• Temperature control: PID1
• Setting the resolution of the LED temperature display °C: 0.1
• Class III (FL) according to DIN 12876-1
• Bath lid and drain tap included
• Removable ventilation grid
• Refrigeration unit without side vents
• Integrated pump connection M16×1
• Space-saving cooling coil design provides more usable space in the bath tank
• Early warning system for low liquid level
• Refrigerant R290

High-performance ultrasonic cleaner for versatile applications

The proven and particularly robust SONOREX ultrasonic baths clean thoroughly and gently by means of intensive cavitation bubbles, even in the hard-to-reach places of the cleaning objects.

A user-friendly rotary handle control is used for easy adjustment of the cleaning time. Matching baskets, lids and cleaning and disinfection concentrates are available as accessories for optimally coordinated ultrasonic cleaning.

The SONOREX TECHNIK range currently consists of 4 series with common characteristics:

• welded stainless steel cleaning tank, 2 mm
• overflow gutter: combined with an oil separator and or a filtering system to continuously remove dirt, oils and grease floating on the surface of the tank
• cleaning fluid filling level mark, facilitates dosing
• welded drain with three-way ball valve for emptying or filling the tank and connecting a filtration system
• additional drain for connecting an oil separator and draining the overflow gutter
• heating: all models are available with (UH) or without (U) heating: on / off with control indicator, thermostatic, adjustable from 30 to 80 ° C
• case protected against drops of water in stainless steel
• for baskets, possibility of having a motorized lift with agitation function
• possibility of making sets of 2 to 5 stations with ultrasonic bath, rinsing bath, drying tank with a motorized translator / elevator / agitator
• straight tank bottom
• garden tube in the tank opposite the overflow gutter to create a flow on the surface of the bath that drains floating contamination, oils and grease from the surface of the bath into the overflow weir.
• safety float switch as protection for heating and ultrasound against dry running.
• feet adjustable in height for leveling on uneven supports.
• ultrasonic generator (integrated): frequency 40 or 25 kHz
• 40 kHz = more penetrating, 25 kHz = more powerful but noisier

Drain pump to convert an appliance with a drain valve into a version equipped with a drain pump.
• For installations without a floor drain

Machine affiliation: Can be used for PLW 8617 devices.

A BINDER FD series Avantgarde.Line heating oven is always used when fast drying and sterilization is required. Thanks to its fully homogeneous temperature distribution, quick dynamics and powerful fan, this heating oven saves valuable time.
Benefits
• Best energy efficiency on the market
• Excellent temporal and spatial temperature accuracy
• USB connection for recording data
• Temperature range up to +300 °C
Important characteristics
• Temperature range: +10 °C above ambient temperature to +300 °C
• High temperature accuracy thanks to APT.line™ technology
• Forced convection
• Controller with LCD display
• Electromechanical control of the exhaust air flap
• 2 chrome-plated racks
• Units up to 115 L are stackable
• Class 2 independent temperature safety device (DIN 12880) with visual temperature alarm
• Ergonomic handle design
• USB port for recording data

Orbital shaken bioreactor for single-use bags with a working volume up to 2500 litres
The next generation of manufacturing-scale orbital shaken bioreactor (OSB) SB2500-Z is now available for the cultivation of human, mammalian, plant, and insect cells in a single-use bag. The bioreactor system has a working volume of 500 to 2500 liters. This user-friendly system has comparatively short set-up times and can be easily deployed in production. The SB2500-Z complies with GMP requirements and regulations.

Performance characteristics

• Large range of working volume: 500-2500 L

• Cultivation of human, mammalian, plant, and insect cells

• User-friendly & fast and simple set-up

• 3D single-use bag

• Trouble-free scale-up

• Online measurement and control of pH and DO

• Qualification for GMP production processes

Single-use bag for a fast and simple set up
The gamma irradiated 3D single-use bag for the Kühner orbital shaken bioreactor requires no additional mixing device and is therefore light and easy to handle. This enables quick set up times and eliminates elaborate cleaning and sterilizing procedures. The single-use bag has a working volume from 500 liters up to 2500 liters. Various ports are incorporated to allow inoculation, feeding, sampling, pH regulation, and harvesting. Two optical sensors each for pH and for DO measurement are built in. Customized bags are easily available on request.

Orbital motion
The orbital motion of the SB2500-Z ensures efficient liquid mixing with low localized power input per unit volume. It allows high oxygen transfer rates with low shear forces. Mechanical stress on the cells is reduced thanks to bubble-free surface gassing with almost no frothing.

Trouble free scale-up
Another advantage of the SB2500-Z is the easy scale-up from microtiter plates over shake flasks to shaken bioreactors all the way up to 2500 liters. The consistent hydro-dynamics of shaken bioreactors provide reproducible cultivation conditions throughout the scaling process.

Good Manufacturing Practice (GMP) and IQ/OQ Documentation
The SB2500-Z complies with GMP requirements and regulations. Kuhner products have established a global reputation of excellence under GMP requirements. Documentation, development and production along with the full life cycle of our products are continuously enhanced to match the requirements of 21 CFR and GAMP 5.
IQ-OQ (Installation Qualification and Operation Qualification), an equipment qualification required for GMP procedures, is available from Kuhner and qualification services can also be provided at the customer's premises.
We subject all our shaking machines to an elaborate final test before delivery and send the test protocols to our customers.

Reliable and monitored drive system
The shaking unit of the SB2500-Z uses a robust and long-lasting drive system which guarantees accurate control of the orbital speed and low energy consumption. The drive system (agitation) requires zero bag penetrations and runs without belts, meaning no abrasion or particle generation, an important factor for production processes in cleanrooms. Motor-specific parameters are constantly monitored, allowing for predictive maintenance and failure prevention. The entire drive unit may be exchanged with a process in place in less than 2 hours.

Control unit
The bespoke control unit, designed by Kuhner, uses the latest touch-screen technology and Siemens SCADA for data recording, calibration, programming and controlling. Technical controls for 21 CFR Part 11 compliance are built into the software.

Temperature regulation
The SB2500-Z can be electrically heated or (optionally) cooled. If cooling is chosen as an option, a cooling ring is embedded in the base plate of the SB2500-Z. Cooling is achieved by connecting an external cooling device. An integrated valve, controlled by the software, regulates the set point temperature. Temperature ramps are easily programmed and processed.

Online measurement and control of pH and DO (dissolved oxygen)
The single use bag has built in pre-calibrated, optical sensors for pH and DO (two of each). The duplex online measurement of both parameters in the medium ensures greater process safety. The pH value can be controlled by the addition of acid/base via peristaltic pumps or stabilized via dosage of CO2. To control the DO, the gas flow of the inlet gas can be increased or decreased, the percentage of oxygen in the inlet gas can be varied (via the gas mixing device), and the shaker speed can be adjusted.

Pumping system
There are three peristaltic pumps, which can be placed external, mobile and can be controlled by the bioreactor software. The control unit incorporates two smaller and one large peristaltic pump. This enables simple regulation of the pH value, feeding and the transfer of the culture media for downstream processing.

Gas mixing (FlowCon)
The SB2500-Z has an integrated gas mixing device (FlowCon). Whether stabilizing the pH with CO2, or preventing low dissolved oxygen concentrations, the gas mixer meets all user needs. Four mass flow controllers ensure highly accurate and reproducible gas mixing. An integrated pressure sensor prevents over pressure in the bioreactor by reducing the gas flow in the first step and shutting off the gas flow in the second step. Step limits can be freely programmed by the user. There is also another pressure sensor directly connected to the bag via the filter. Integrated gas filters ensure interference free and long operating times for the FlowCon.

Filter heater
A height adjustable filter heater, with up to two exhaust filters, is installed above the vessel. Special emphasis has been placed on developing a user-friendly unit. The filter heater combats any water vapor condensation in the outlet air which might cause the membranes to block. The temperature is monitored and controlled by the Siemens SCADA software of the control unit.

The Sigma 2‑16P is the right answer for virtually every task in everyday lab work. This all-purpose centrifuge is versatile in use and fits in every lab thanks to its compact design. With an extensive range of rotors and accessories and high RCF values up to 20,627 x g, it is suitable for a wide variety of applications.

What makes the Sigma 2‑16P benchtop centrifuge so attractive?

With a wide range of fixed-angle and swing-out rotors, this all-purpose centrifuge can hold PCR tubes, test tubes, round-bottom tubes, culture tubes and microtiter plates. This extensive range is rounded out by a haematocrit rotor.

The Sigma 2‑16P provides extraordinary capacity with 4 x 100 ml in a swing-out rotor or 6 x 50 ml in a fixed-angle rotor.

Up to 50 different routine protocols can be stored in program memory and easily retrieved. Ten selectable acceleration and braking curves support the optimisation of separation processes.

Applications: Hospitals, Veterinary clinics, Food labs, Universities & colleges, Pharmaceutical labs, Cell culture labs

The Sigma 2‑16P is available as a refrigerated centrifuge and as a refrigerated and heated centrifuge.

The Sigma 1‑16 K microcentrifuge stands out with its space-saving design, high-quality finishing and excellent performance characteristics.

The extensive range includes rotors for PCR strips, filter tubes and 2 ml or 5 ml microlitre tubes, and a rotor for centrifuging microhaematocrit capillary tubes. Its strong performance and range of rotors make the Sigma 1‑16 K ideal for microbiological and protein biochemistry applications and clinical chemistry applications.

What makes the Sigma 1‑16K microcentrifuge so attractive?

The Sigma 1‑16K features RCF values greater than 20,600 x g, short acceleration and braking times, a high-grade stainless steel bowl, and a motorised lid lock for effortless closing. Further highlights include the ability to store ten standard programs, a closable biosafe rotor with a capacity of 36 x 2 ml, and a rotor for 12 x 5 ml test tubes.

Product options:
• IVD
• Centrifuge package with 24 x 2 ml PP rotor
• Biosafe 36 x 2 ml rotor

Applications: Hospitals, Veterinary clinics, Food labs, Universities & colleges, Pharmaceutical labs, Cell culture labs

The Sigma 1‑16K is also available as the Sigma 1‑16 unrefrigerated centrifuge and as an IVD model.